back to PRO homepage
  Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology Report - Myc protein

PR:000000020 - http://purl.obolibrary.org/obo/PR_000000020
Ontology Information
PRO ID PR:000000020 Show OBO stanza / PAF
PRO name Myc protein
Synonyms
Other: BROAD: bHLH clade B | bHLH class III
Definition A protein that belongs to the clade B of the bHLH proteins (see PMID:20219281) with a core domain composition consisting of a Myc amino-terminal region (Pfam:PF01056) regulatory domain (known as TAD domain), a helix-loop-helix DNA-binding domain (Pfam:PF00010). Some members such as c-Myc contains an addition C-terminal Myc leucine zipper domain (Pfam:PF02344). Myc proteins participate in the regulation of cell proliferation, cell differentiation, and apoptosis. [PMID:16113099, PMID:16537894, PMID:16543245, PRO:CNA]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000000020
Myc protein
acts_upstream_of_or_within GO:0042127 regulation of cell population proliferation PIRSF:PIRSF001705
enables GO:0005515 protein binding PIRSF:PIRSF001705
enables GO:0003677 DNA binding PIRSF:PIRSF001705

top