PRO Entry Report - PR:000000023

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RACE-PRO

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Protein Ontology Report - retinoblastoma-like protein

PR:000000023 - http://purl.obolibrary.org/obo/PR_000000023

Annotations

Ontology Information
PRO ID	PR:000000023 Show OBO stanza / PAF
PRO name	retinoblastoma-like protein
Definition	A protein that has a core domain composition consisting of a Retinoblastoma-associated protein A domain (Pfam:PF01858) followed by a Retinoblastoma-associated protein B domain (Pfam:PF01857). The retinoblastoma-like proteins are key regulators of entry into cell division. They are directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. [PRO:CNA]
PRO Category	family
Parent	PR:000000001 protein
Term Hierarchy Visualization	DAG OLS Cytoscape

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000000023 retinoblastoma-like protein	acts_upstream_of_or_within	GO:0051726 regulation of cell cycle	PIRSF:PIRSF037408
PR:000000023 retinoblastoma-like protein	enables	GO:0005515 protein binding	PIRSF:PIRSF037408

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