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Protein Ontology Report - smad protein

PR:000000027 -
Ontology Information
PRO ID PR:000000027 Show OBO stanza / PAF
PRO name smad protein
Definition A protein with core domain composition consisting of one MH1 domain (Pfam:PF03165) at the N terminus and one MH2 domain (Pfam:PF03166) at the C-terminus, separated by a non-conserved linker region. Smad proteins are mediators of signal transduction in transforming growth factor beta (TGF-beta) superfamily pathways. [PRO:CNA]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape

Functional Annotation
PRO Term GO Annotation Evidence
smad protein
acts_upstream_of_or_within GO:0007165 signal transduction PIRSF:PIRSF037286
acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PIRSF:PIRSF037286
enables GO:0005515 protein binding PIRSF:PIRSF037286