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Protein Ontology Report - RBX1

PR:000000043 - http://purl.obolibrary.org/obo/PR_000000043
Ontology Information
PRO ID PR:000000043 Show OBO stanza / PAF
PRO name E3 ubiquitin-protein ligase RBX1
Synonyms
PRO-short-label: EXACT: RBX1
Gene-based: RELATED: RNF75 | ROC1
Other: EXACT: E3 ubiquitin-protein transferase RBX1 | RING finger protein 75 | RING-box protein 1 | protein ZYP | rbx1 | regulator of cullins 1
Definition A RING-box protein 1 related protein that is a translation product of the human RBX1 gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000027961 RING-box protein 1 related protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 7
sequence 1 organism-sequence 2
modification 2 organism-modification 1
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

RBX1 forms found in complexes
RBX1 Component Complexes
PR:000026756 hRBX1/InitMet- PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human)
PR:000026756 hRBX1/InitMet- PR:000026771 SCF beta-TrCP complex (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000043
RBX1
acts_upstream_of_or_within GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PIRSF:PIRSF500724
part_of GO:0019005 SCF ubiquitin ligase complex PIRSF:PIRSF500724
PR:P62877-1
hRBX1/iso:1
acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PMID:10230407
acts_upstream_of_or_within GO:0045116 protein neddylation PMID:15966899
acts_upstream_of_or_within GO:0006606 protein import into nucleus PMID:11027288
enables GO:0005515 protein binding with PR:Q13616-1 hCUL1/iso:1 PMID:11961546
enables GO:0005515 protein binding with PR:Q9EQW6 mOLIG2 PMID:11027288
part_of GO:0031462 Cul2-RING ubiquitin ligase complex PMID:15966899
part_of GO:0000151 ubiquitin ligase complex PMID:16325183
part_of GO:0019005 SCF ubiquitin ligase complex PMID:15966899
part_of GO:0000151 ubiquitin ligase complex PMID:17217622

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