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Protein Ontology Report - SKP1

PR:000000045 - http://purl.obolibrary.org/obo/PR_000000045
Ontology Information
PRO ID PR:000000045 Show OBO stanza / PAF
PRO name S-phase kinase-associated protein 1A
Synonyms
PRO-short-label: EXACT: SKP1
Gene-based: RELATED: EMC19 | OCP2 | SKP1A | TCEB1L
Other: EXACT: OCP-2 | OCP-II | RNA polymerase II elongation factor-like protein | SIII | cyclin-A/CDK2-associated protein p19 | organ of Corti protein 2 | organ of Corti protein II | p19A | p19skp1 | transcription elongation factor B
Definition An E3 ubiquitin ligase SFC complex Skp1 subunit that is a translation product of the human SKP1 gene or a 1:1 ortholog thereof. This gene has 5 conserved protein coding exons. [PRO:CNA]
PRO Category gene
Parent PR:000000002 E3 ubiquitin ligase SFC complex Skp1 subunit
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 6
sequence 2 organism-sequence 3
modification 2 organism-modification 1
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

SKP1 forms found in complexes
SKP1 Component Complexes
PR:000026755 hSKP1/InitMet- PR:000026772 SCF(Skp2) complex (human)
PR:000026755 hSKP1/InitMet- PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human)
PR:000026755 hSKP1/InitMet- PR:000026771 SCF beta-TrCP complex (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:P63208-1
hSKP1/iso:1
enables GO:0005515 protein binding with PR:Q13616-1 hCUL1/iso:1 PMID:12609982
part_of GO:0019005 SCF ubiquitin ligase complex PMID:11961546, PMID:12481031, PMID:16797541, PMID:17098746
PR:Q9WTX5-1
mSKP1/iso:1
enables GO:0005515 protein binding with PR:P63087-1 mPPP1CC/iso:Gamma-1 PMID:17274640
enables GO:0005515 protein binding with PR:P62137-1 mPPP1CA/iso:1 PMID:17274640
part_of GO:0019005 SCF ubiquitin ligase complex PMID:12665572

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