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Protein Ontology Report - TGFB2

PR:000000183 - http://purl.obolibrary.org/obo/PR_000000183
Ontology Information
PRO ID PR:000000183 Show OBO stanza / PAF
PRO name TGF-beta 2
Synonyms
PRO-short-label: EXACT: TGFB2
Other: EXACT: BSC-1 cell growth inhibitor | G-TSF | TGF-beta-2 | cetermin | glioblastoma-derived T-cell suppressor factor | polyergin
Definition A TGF-beta that is a translation product of the human TGFB2 gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000046 TGF-beta
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 2 organism-sequence 5
modification 8 organism-modification 6
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P61812-1
hTGFB2/iso:A
enables GO:0046982 protein heterodimerization activity PMID:2119582
PR:P61812-2
hTGFB2/iso:B
enables GO:0046982 protein heterodimerization activity PMID:17845732
located_in GO:0045177 apical part of cell PMID:17845732
PR:000036531
mTGFB2/iso:A/Clv:2
enables GO:0005515 protein binding with PR:Q07475 mNREP PMID:14985127
PR:000036530
hTGFB2/iso:A/Clv:1
acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:3162913
acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation PMID:15944186
enables GO:0005160 transforming growth factor beta receptor binding PMID:16227582
enables GO:0001540 amyloid-beta binding PMID:16227582
enables GO:0042803 protein homodimerization activity PMID:2119582, PMID:3476488
located_in GO:0005615 extracellular space PMID:3162913
PR:000036533
hTGFB2/iso:A/Clv:3
enables GO:0042803 protein homodimerization activity PMID:3476488
located_in GO:0005615 extracellular space PMID:3162913
PR:000036532
hTGFB2/iso:A/Clv:2
part_of GO:0032991 protein-containing complex PMID:3162913
PR:000036535
hTGFB2/iso:B/Clv:2
located_in GO:0005615 extracellular space PMID:1777240
PR:000036534
hTGFB2/iso:B/Clv:1
located_in GO:0005615 extracellular space PMID:1777240
PR:000000183
TGFB2
acts_upstream_of_or_within GO:0008283 cell population proliferation PANTHER:PTHR11848:SF33
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0045177 apical part of cell PR:P61812-2 hTGFB2/iso:B

PMID:17845732
GO:0005615 extracellular space PR:000036530 hTGFB2/iso:A/Clv:1

PMID:3162913
PR:000036533 hTGFB2/iso:A/Clv:3

PMID:3162913
PR:000036534 hTGFB2/iso:B/Clv:1

PMID:1777240
PR:000036535 hTGFB2/iso:B/Clv:2

PMID:1777240

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