PRO Entry Report - PR:000000183

Protein Forms Annotations

Ontology Information

PRO ID

PR:000000183 Show OBO stanza / PAF

PRO name

TGF-beta 2

Synonyms

PRO-short-label:	EXACT:	TGFB2
Other:	EXACT:	BSC-1 cell growth inhibitor \| G-TSF \| TGF-beta-2 \| cetermin \| glioblastoma-derived T-cell suppressor factor \| polyergin

Definition

A TGF-beta that is a translation product of the human TGFB2 gene or a 1:1 ortholog thereof. [PRO:CNA]

PRO Category

gene

Parent

Terms by PRO Category

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OLS

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Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:P61812-1 hTGFB2/iso:A	enables	GO:0046982 protein heterodimerization activity	PMID:2119582
PR:P61812-2 hTGFB2/iso:B	enables	GO:0046982 protein heterodimerization activity	PMID:17845732
PR:P61812-2 hTGFB2/iso:B	located_in	GO:0045177 apical part of cell	PMID:17845732
PR:000036531 mTGFB2/iso:A/Clv:2	enables	GO:0005515 protein binding with PR:Q07475 mNREP	PMID:14985127
PR:000036530 hTGFB2/iso:A/Clv:1	acts_upstream_of_or_within	GO:0008285 negative regulation of cell population proliferation	PMID:15944186
	acts_upstream_of_or_within	GO:0007179 transforming growth factor beta receptor signaling pathway	PMID:3162913
	enables	GO:0001540 amyloid-beta binding	PMID:16227582
	enables	GO:0042803 protein homodimerization activity	PMID:2119582, PMID:3476488
	enables	GO:0005160 transforming growth factor beta receptor binding	PMID:16227582
	located_in	GO:0005615 extracellular space	PMID:3162913
PR:000036533 hTGFB2/iso:A/Clv:3	enables	GO:0042803 protein homodimerization activity	PMID:3476488
PR:000036533 hTGFB2/iso:A/Clv:3	located_in	GO:0005615 extracellular space	PMID:3162913
PR:000036532 hTGFB2/iso:A/Clv:2	part_of	GO:0032991 protein-containing complex	PMID:3162913
PR:000036535 hTGFB2/iso:B/Clv:2	located_in	GO:0005615 extracellular space	PMID:1777240
PR:000036534 hTGFB2/iso:B/Clv:1	located_in	GO:0005615 extracellular space	PMID:1777240
PR:000000183 TGFB2	acts_upstream_of_or_within	GO:0008283 cell population proliferation	PANTHER:PTHR11848:SF33

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