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Protein Ontology Report - ROCK1/iso:1

PR:000000307 -
Ontology Information
PRO ID PR:000000307 Show OBO stanza
PRO name Rho-associated protein kinase 1 isoform 1
PRO-short-label: EXACT: ROCK1/iso:1
Other: EXACT: ROCK1 sequence 1
Definition A Rho-associated protein kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13464-1 or a 1:1 ortholog thereof. [PRO:CNA, PRO:DAN]
Comment Note: In resting cells, the C-terminal Rho-binding and PH domain mask the protein kinase catalytic domain, activation occurs through a conformational change.
PRO Category sequence
Parent PR:000000120 Rho-associated protein kinase 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

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Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment