PRO ID |
PR:000000308
Show OBO stanza
|
PRO name |
Rho-associated protein kinase 2 isoform 1 |
Synonyms |
PRO-short-label: |
EXACT: |
ROCK2/iso:1 |
|
Definition |
A Rho-associated protein kinase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75116-1 or a 1:1 ortholog thereof.
[PRO:CNA, PRO:DAN]
|
Comment |
Note: In resting cells, the C-terminal Rho-binding and PH domain mask the protein kinase catalytic domain, activation occurs through a conformational change. |
PRO Category |
sequence |
Parent |
PR:000000121 Rho-associated protein kinase 2 |
Term Hierarchy Visualization |
DAG
OLS
Cytoscape
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