back to PRO homepage
  Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download
 PRO tracker
 PRO Consortium

Protein Ontology Report - SMURF1

PR:000000361 -
Ontology Information
PRO ID PR:000000361 Show OBO stanza / PAF
PRO name E3 ubiquitin-protein ligase SMURF1
PRO-short-label: EXACT: SMURF1
Gene-based: RELATED: KIAA1625
Other: EXACT: HECT-type E3 ubiquitin transferase SMURF1 | SMAD ubiquitination regulatory factor 1 | SMAD-specific E3 ubiquitin-protein ligase 1 | smad ubiquitination regulatory factor 1
Definition A smad ubiquitination regulatory factor that is a translation product of the human SMURF1 gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000127 smad ubiquitination regulatory factor
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 3
modification 0 organism-modification 2
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:10458166
acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:14711801
located_in GO:0005622 intracellular anatomical structure PMID:14711801
acts_upstream_of_or_within GO:0036211 protein modification process PMID:10458166
acts_upstream_of_or_within GO:0030579 ubiquitin-dependent SMAD protein catabolic process PMID:12857866
acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PMID:10458166
enables GO:0004842 ubiquitin-protein transferase activity PMID:10458166
enables GO:0005515 protein binding PMID:11278251, PMID:16299379
located_in GO:0005622 intracellular anatomical structure PMID:10458166
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005622 intracellular anatomical structure PR:Q9CUN6-1 mSMURF1/iso:Short

PR:Q9HCE7-2 hSMURF1/iso:Short