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Protein Ontology Report - hSMAD2/var:R133C

PR:000000470 -
Ontology Information
PRO ID PR:000000470 Show OBO stanza / PAF
PRO name smad2 sequence variant R133C (human)
PRO-short-label: EXACT: hSMAD2/var:R133C
PRO-proteoform-std: NARROW: UniProtKB:Q15796-1, Arg-133, CHEBI:29950
Other: EXACT: smad2 sequence variant 1 (human)
Definition A mothers against decapentaplegic homolog 2 (human) that has a Cys residue at the position equivalent to Arg-133 of the amino acid sequence represented by UniProtKB:Q15796-1. Example: UniProtKB:Q15796-1, Arg-133, CHEBI:29950. [PMID:8752209, PRO:CNA, PRO:DAN]
PRO Category organism-sequence
Parent PR:Q15796 mothers against decapentaplegic homolog 2 (human)
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
Arg-133, CHEBI:29950
associated_with_disease_progression DOID:5672 large intestine cancer PMID:8752209
capable_of NOT GO:0003713 transcription coactivator activity PMID:8752209
participates_in GO:0007165 signal transduction PMID:8752209
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007165 signal transduction PR:000000470 hSMAD2/var:R133C
Arg-133, CHEBI:29950