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Protein Ontology Report - ROCK1/iso:1/Clv:1

PR:000000563 -
Ontology Information
PRO ID PR:000000563 Show OBO stanza
PRO name Rho-associated protein kinase 1 isoform 1 cleaved 1
PRO-short-label: EXACT: ROCK1/iso:1/Clv:1
Other: EXACT: constitutively active ROCK-1
Definition A Rho-associated protein kinase 1 isoform 1 that has been processed by caspase-3 downstream the sequence motif DETD, removing the inhibitory C-terminus. [PMID:11283607, PMID:16983089]
Comment Note: This form has been found significantly elevated in mouse myopathy model and human heart failure patients.
PRO Category modification
Parent PR:000000307 Rho-associated protein kinase 1 isoform 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment