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Protein Ontology Report - hTGFB1/var:C225R/Clv:2

PR:000000626 -
Ontology Information
PRO ID PR:000000626 Show OBO stanza / PAF
PRO name TGF-beta 1 sequence variant C225R cleaved 2 (human)
PRO-short-label: EXACT: hTGFB1/var:C225R/Clv:2
PRO-proteoform-std: EXACT: UniProtKB:P01137, 30-278, Cys-225, CHEBI:29952
Other: EXACT: TGF-beta 1 sequence variant 6 cleaved 2 (human)
Definition A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, Cys-225, CHEBI:29952. [PMID:11278244, PRO:CNA, PRO:DAN]
PRO Category organism-modification
Parent PR:000021906 TGF-beta 1 sequence variant C225R, signal peptide removed form (human)
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
Cys-225, CHEBI:29952
has_agent SO:0001561 polypeptide_partial_loss_of_function PMID:11278244