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Protein Ontology Report - SMAD3/iso:1/Phos:2

PR:000000659 - http://purl.obolibrary.org/obo/PR_000000659
Ontology Information
PRO ID PR:000000659 Show OBO stanza
PRO name smad3 isoform 1 phosphorylated 2
Synonyms
PRO-short-label: EXACT: SMAD3/iso:1/Phos:2
Definition A smad3 isoform 1 phosphorylated form in which the phosphorylation occurs at the N-terminal Px[ST]P motif and the clusters of [ST]P motifs within the MH1-MH2 domain linker region by G1 cyclin-dependent kinases (CDK4 and CDK2) leading to CDK inhibition of its transcriptional activity and antiproliferative function. Example: UniProtKB:Q8BUN5-1, Thr-8/Thr-179, MOD:00047, Ser-213, MOD:00046. [PMID:15241418, PRO:CNA, PRO:DAN]
PRO Category modification
Parent PR:000000578 smad3 isoform 1 phosphorylated form
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

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