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Protein Ontology Report - CNGB3

PR:000000697 - http://purl.obolibrary.org/obo/PR_000000697
Ontology Information
PRO ID PR:000000697 Show OBO stanza / PAF
PRO name cyclic nucleotide-gated cation channel beta-3
Synonyms
PRO-short-label: EXACT: CNGB3
Gene-based: RELATED: Cng6
Other: EXACT: CNG channel beta-3 | cone photoreceptor cGMP-gated channel subunit beta | cyclic nucleotide-gated channel beta-3 | cyclic nucleotide-gated channel subunit CNG6
BROAD: cyclic nucleotide-gated cation channel modulatory subunit
Definition A cyclic nucleotide-gated channel beta subunit that is a translation product of the human CNGB3 gene or a 1:1 ortholog thereof. Many members of this class are subunits of the cone cyclic nucleotide-gated cation channel, which generates the light-evoked electrical responses of cone photoreceptors. [PRO:CNA]
PRO Category gene
Parent PR:000000674 cyclic nucleotide-gated channel beta subunit
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 2
sequence 3 organism-sequence 4
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000752
hCNGB3/var:S435F
Ser-435, CHEBI:29997
associated_with_disease_progression DOID:13911 achromatopsia PMID:10888875, PMID:10958649
PR:Q9JJZ9-1
mCNGB3/iso:1
enables GO:0005515 protein binding PMID:10662822
enables GO:0005223 intracellular cGMP-activated cation channel activity PMID:10662822
located_in GO:0005886 plasma membrane PMID:10662822
located_in GO:0001750 photoreceptor outer segment PMID:15634774
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005886 plasma membrane PR:Q9JJZ9-1 mCNGB3/iso:1

PMID:10662822
GO:0001750 photoreceptor outer segment PR:Q9JJZ9-1 mCNGB3/iso:1

PMID:15634774

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