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Protein Ontology Report - fam:Kchan_sub-KCNG

PR:000000701 - http://purl.obolibrary.org/obo/PR_000000701
Ontology Information
PRO ID PR:000000701 Show OBO stanza / PAF
PRO name modulatory voltage-gated potassium channel subunit KCNG
Synonyms
PRO-short-label: EXACT: fam:Kchan_sub-KCNG
Other: RELATED: silent subunit
Definition A voltage-gated potassium channel alpha subunit that is a modulator of the shab-related potassium channels (Kv2). Similarly to KCNF1, KCNV and KCNS subunits, KCNG subunits are not able to form functional channels on their own. Also in common with these modulatory subunits, it lacks the conserved PxP motif located in the distal part of S6. In this class the motif is PxT. The alteration of the PxP motif seems to be an important determinant of the regulatory function of modulatory subunits. [PMID:9305895]
PRO Category family
Parent PR:000000685 voltage-gated potassium channel alpha subunit
Term Hierarchy Visualization DAG     OLS     Cytoscape


Functional Annotation
PRO Term GO Annotation Evidence
PR:000000701
fam:Kchan_sub-KCNG
enables GO:0015459 potassium channel regulator activity PIRSF:PIRSF500980

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