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Protein Ontology Report - ITGAX

PR:000001013 -
Ontology Information
PRO ID PR:000001013 Show OBO stanza
PRO name integrin alpha-X
PRO-short-label: EXACT: ITGAX
Gene-based: RELATED: CD11C
Other: EXACT: CD11 antigen-like family member C | CD11c | Leu M5 | leukocyte adhesion glycoprotein p150,95 alpha chain | leukocyte adhesion receptor p150,95
Definition An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. [UniProtKB:P20702]
Comment Requested by=CL.
PRO Category gene
Parent PR:000001005 integrin alpha with A domain
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 2
sequence 0 organism-sequence 0
modification 1 organism-modification 1
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment