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Protein Ontology Report - erm protein

PR:000001030 -
Ontology Information
PRO ID PR:000001030 Show OBO stanza / PAF
PRO name erm protein
Definition A protein that contain 3 domains, an N-terminal globular domain, an extended alpha-helical domain, and a charged C-terminal domain. Ezrin, radixin and merlin also contain a polyproline region between the helical and C-terminal domains. The N-terminal domain is highly conserved, and is also found in merlin, band 4.1 proteins and members of the band 4.1 superfamily. ERM proteins are involved in crosslinking actin filaments with plasma membranes. [InterPro:IPR011259]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape

Functional Annotation
PRO Term GO Annotation Evidence
erm protein
enables GO:0008092 cytoskeletal protein binding PIRSF:PIRSF002305