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Protein Ontology Report - TLR9

PR:000001160 -
Ontology Information
PRO ID PR:000001160 Show OBO stanza
PRO name Toll-like receptor 9
PRO-short-label: EXACT: TLR9
Gene-based: RELATED: UNQ5798/PRO19605
Other: EXACT: CD289
Definition A Toll-like receptor that is a translation product of the human TLR9 gene or a 1:1 ortholog thereof. Non-methylated CpG motifs, present in viral and bacterial DNA, are one of many pathogen-associated molecular patterns (PAMP) recognized by the mammalian innate immune system. Recognition of this PAMP occurs through a specific interaction with Toll-like receptor 9 and this interaction can induce cytokine responses that influence both innate and adaptive immune responses. [PMID:11022119]
PRO Category gene
Parent PR:000001096 Toll-like receptor
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 0 organism-sequence 5
modification 0 organism-modification 1
union 0
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Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment