| PRO ID |
PR:000001315
Show OBO stanza
|
| PRO name |
frizzled-like G-protein coupled receptor |
| Synonyms |
| PRO-short-label: |
EXACT: |
fam:frizzled |
| Other: |
EXACT: |
class F G-protein coupled receptor |
|
| Definition |
A G-protein coupled receptor with core architecture consisting of an Fz domain (Pfam:PF01392), also known as Frizzled CRD (cysteine rich domain), followed by a Frizzled/Smoothened family membrane region (Pfam:PF01534), which includes 7 transmembrane helices, and a cytoplasmic domain containing the motif Lys-Thr-x-x-x-Trp. They generally function as cell-surface receptors for Wnts.
[InterPro:IPR015526, PRO:DAN, PRO:WCB]
|
| Comment |
Classification based on GRAFS system. [PMID:12761335] |
| PRO Category |
family |
| Parent |
PR:000030035 G-protein coupled receptor |
| Term Hierarchy Visualization |
 DAG
 OLS
Cytoscape
|
