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Protein Ontology Report - PTGER3

PR:000001659 -
Ontology Information
PRO ID PR:000001659 Show OBO stanza / PAF
PRO name prostaglandin E2 receptor EP3 subtype
PRO-short-label: EXACT: PTGER3
Gene-based: RELATED: Ptgerep3
Other: EXACT: PGE receptor EP3 subtype | PGE2 receptor EP3 subtype | PGE2-R | prostaglandin E2 receptor EP3 | prostanoid EP3 receptor
Definition A prostanoid receptor that is a translation product of the human PTGER3 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is the most ubiquitous of the prostaglandin E2 receptors, mediating contraction of gastrointestinal, uterine, and vascular smooth muscle, inhibition of neurotransmitter release from autonomic nerves, inhibition of lipolysis in adipocytes, inhibition of acid secretion from gastric mucosa, and inhibition of water reabsorption in kidney. [PMID:7938166, PRO:WCB]
PRO Category gene
Parent PR:000001549 prostanoid receptor
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 3 organism-sequence 18
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
enables GO:0004957 prostaglandin E receptor activity MGI:64071, PMID:8381413