PRO ID |
PR:000001662
Show OBO stanza
|
PRO name |
proteinase-activated receptor 2 |
Synonyms |
PRO-short-label: |
EXACT: |
F2RL1 |
Gene-based: |
RELATED: |
GPR11 | Gpcr11 | PAR2 |
Other: |
EXACT: |
G-protein coupled receptor 11 | PAR-2 | coagulation factor II receptor-like 1 | thrombin receptor-like 1 |
|
Definition |
A proteinase-activated receptor that is a translation product of the human F2RL1 gene or a 1:1 ortholog thereof. It is activated by trypsin and trypsin-like proteinases, which cleave the mature peptide, exposing a new amino end. The six new N-terminal residues act as a tethered ligand that induces activity.
[PMID:7556175, PRO:WCB]
|
PRO Category |
gene |
Parent |
PR:000001550 proteinase-activated receptor |
Terms by PRO Category |
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Organism-Independent |
Organism-Specific |
Category |
Number of Terms |
Category |
Number of Terms |
gene
|
1 |
organism-gene
|
3 |
sequence
|
0 |
organism-sequence
|
0 |
modification
|
0 |
organism-modification
|
0 |
union
|
0 |
|
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