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Protein Ontology Report - CD59-like

PR:000001809 - http://purl.obolibrary.org/obo/PR_000001809
Ontology Information
PRO ID PR:000001809 Show OBO stanza / PAF
PRO name CD59-like glycoprotein
Synonyms
PRO-short-label: EXACT: CD59-like
Definition A protein that is a translation product of the human CD59 gene, a 1:1 ortholog thereof, or pro-orthologs thereof. [PRO:WCB]
Comment Requested by=CL. Pro-orthology refers to, in this case, after-speciation gene duplication in the non-human species (aka 1:many orthology). This gene is present as a single copy in human and has undergone a lineage-specific duplication in mouse. CD59 antigen has a core architecture consisting of one UPAR/Ly-6 domain (Pfam:PF00021), a small domain of about 70 amino acids and containing 5 conserved disulfide bonds. It is both N- and O-glycosylated and is a GPI-anchored protein that releases soluble forms in some tissues.
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 4 organism-gene 4
sequence 1 organism-sequence 2
modification 3 organism-modification 33
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000001809
CD59-like
has_part Pfam:PF00021 u-PAR/Ly-6 domain
PR:P13987-1
hCD59/iso:1
has_role CHEBI:59163 biomarker PMID:18829504

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