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Protein Ontology Report - IKZF1

PR:000001811 -
Ontology Information
PRO ID PR:000001811 Show OBO stanza / PAF
PRO name DNA-binding protein Ikaros
PRO-short-label: EXACT: IKZF1
Gene-based: RELATED: IK1 | IKAROS | LYF1 | ZNFN1A1 | Zfpn1a1
Other: EXACT: Ikaros family zinc finger protein 1 | lymphoid transcription factor LyF-1
Definition An Ikaros-like zinc finger transcription factor that is a translation product of the human IKZF1 gene or a 1:1 ortholog thereof. [PRO:WCB]
PRO Category gene
Parent PR:000002986 Ikaros-like zinc finger transcription factor
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 6 organism-sequence 15
modification 2 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
acts_upstream_of_or_within GO:0000122 negative regulation of transcription by RNA polymerase II PMID:12617992
acts_upstream_of_or_within GO:0001779 natural killer cell differentiation PMID:7923373
acts_upstream_of_or_within GO:0060041 retina development in camera-type eye MGI:3831471, PMID:18940586
acts_upstream_of_or_within GO:0051138 positive regulation of NK T cell differentiation MGI:1340364, PMID:10366784
enables GO:0046982 protein heterodimerization activity with PR:Q8C208-1 mIKZF4/iso:1 MGI:1333610, PMID:10218586
enables GO:0046982 protein heterodimerization activity with PR:P81183-1|PR:P81183-2 MGI:1203354, PMID:9560339
located_in GO:0005634 nucleus MGI:2652944, PMID:12617992
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:Q03267-1 mIKZF1/iso:VI

MGI:2652944, PMID:12617992