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Protein Ontology Report - caspase-1-like protease

PR:000002195 -
Ontology Information
PRO ID PR:000002195 Show OBO stanza / PAF
PRO name caspase-1-like protease
Definition A protein that is a translation product of a family of genes that includes CASP1, CASP2, CASP4, CASP5, CASP9 and others. The core architecture consists of a Caspase recruitment domain (Pfam:PF00619), Caspase domain (Pfam:PF00656) and a PAAD/DAPIN/Pyrin domain (Pfam:PF02758). Encoded as zymogens, the activated proteins are cysteine proteases typically involved in apoptosis. [PRO:WCB]
PRO Category family
Parent PR:000000001 protein
Term Hierarchy Visualization DAG     OLS     Cytoscape

Functional Annotation
PRO Term GO Annotation Evidence
caspase-1-like protease
has_part Pfam:PF00619 Caspase recruitment domain
has_part Pfam:PF00656 Caspase domain
has_part Pfam:PF02758 PAAD/DAPIN/Pyrin domain