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Protein Ontology Report - CASP1

PR:000002309 -
Ontology Information
PRO ID PR:000002309 Show OBO stanza
PRO name caspase-1
PRO-short-label: EXACT: CASP1
Gene-based: RELATED: IL1BC | IL1BCE
Other: EXACT: CASP-1 | ICE | IL-1 beta-converting enzyme | IL-1BC | interleukin-1 beta convertase | interleukin-1 beta-converting enzyme
BROAD: p45
Definition A caspase-1-like protease that is a translation product of the human CASP1 gene or a 1:1 ortholog thereof. The active form of this protein proteolytically cleaves pro-IL-1beta to its mature, active form. The holoenzyme is a homodimer of catalytic domains, each of which contains the cleaved products caspase-1 p20 and p10 subunits. [PMID:8044845, PRO:WCB]
PRO Category gene
Parent PR:000002195 caspase-1-like protease
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 6 organism-sequence 6
modification 3 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment