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Protein Ontology Report - TANK

PR:000003146 - http://purl.obolibrary.org/obo/PR_000003146
Ontology Information
PRO ID PR:000003146 Show OBO stanza / PAF
PRO name TRAF family member-associated NF-kappa-B activator
Synonyms
PRO-short-label: EXACT: TANK
Gene-based: RELATED: ITRAF | TRAF2
Other: EXACT: I-TRAF
BROAD: TRAF-interacting protein
Definition A protein that is a translation product of the human TANK gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 2
sequence 1 organism-sequence 7
modification 3 organism-modification 2
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

TANK forms found in complexes
TANK Component Complexes
PR:000036091 mTANK/iso:1/K63polyUbiq+ PR:000036099 ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036091 mTANK/iso:1/K63polyUbiq+ PR:000036097 tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036091 mTANK/iso:1/K63polyUbiq+ PR:000036095 K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036091 mTANK/iso:1/K63polyUbiq+ PR:000036093 tbk1:K63-poly-Ub-tank:Ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:P70347 mTANK PR:000036090 tbk1:tank:ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:P70347 mTANK PR:000037313 tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse)
PR:P70347 mTANK PR:000036149 tbk1:tank:ikke complex (mouse)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036149
tbk1:tank:ikke complex (mouse)
participates_in GO:0034138 toll-like receptor 3 signaling pathway PMID:17823124
PR:000037313
tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse)
participates_in GO:0034138 toll-like receptor 3 signaling pathway PMID:12133833, PMID:17327220
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0034138 toll-like receptor 3 signaling pathway PR:000036149 tbk1:tank:ikke complex (mouse)

PMID:17823124
PR:000037313 tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse)

PMID:12133833, PMID:17327220

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