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Protein Ontology Report - IRF7/iso:1/Phos:1

PR:000003281 - http://purl.obolibrary.org/obo/PR_000003281
Ontology Information
PRO ID PR:000003281 Show OBO stanza
PRO name interferon regulatory factor 7 isoform 1 phosphorylated 1
Synonyms
PRO-short-label: EXACT: IRF7/iso:1/Phos:1
Other: EXACT: IRF-7 active form | IRF-7 phosphorylated | phospho IRF7
Definition An interferon regulatory factor 7 isoform 1 phosphorylated form that has been activated by phosphorylation on the Ser residues located in the C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. Example: UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046. [PMID:10893229, PMID:14517278, PMID:20043992, TLR:AMM]
Comment Requested by=TLR.
PRO Category modification
Parent PR:000003280 interferon regulatory factor 7 isoform 1 phosphorylated form
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

IRF7/iso:1/Phos:1 forms found in complexes
IRF7/iso:1/Phos:1 Component Complexes
PR:000027082 hIRF7/iso:1/Phos:1 PR:000027084 IRF3-P:IRF7-P complex (human)
PR:000027082 hIRF7/iso:1/Phos:1 PR:000027086 IRF7-P:IRF7-P complex (human)

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