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Protein Ontology Report - HSPH1

PR:000003410 - http://purl.obolibrary.org/obo/PR_000003410
Ontology Information
PRO ID PR:000003410 Show OBO stanza / PAF
PRO name heat shock protein 105 kDa
Synonyms
PRO-short-label: EXACT: HSPH1
Gene-based: RELATED: HSP105 | HSP110 | KIAA0201
Other: EXACT: 42 degrees C-HSP | HSP-E7I | antigen NY-CO-25 | heat shock 110 kDa protein | heat shock-related 100 kDa protein E7I
Definition An HSPH protein that is a translation product of the human HSPH1 gene or a 1:1 ortholog thereof. [SWAN:PC]
PRO Category gene
Parent PR:000003413 HSPH protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 6
sequence 2 organism-sequence 6
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q61699-2
mHSPH1/iso:HSP105-beta
acts_upstream_of_or_within GO:0061098 positive regulation of protein tyrosine kinase activity MGI:4422145, PMID:19754877
acts_upstream_of_or_within GO:1903751 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide MGI:3822965, PMID:18681888
acts_upstream_of_or_within GO:2001234 negative regulation of apoptotic signaling pathway MGI:3688933, PMID:16857185
acts_upstream_of_or_within GO:1903753 negative regulation of p38MAPK cascade MGI:3822965, PMID:18681888
acts_upstream_of_or_within GO:1903748 negative regulation of establishment of protein localization to mitochondrion MGI:3688933, PMID:16857185
acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI:5607132, PMID:19028714
acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI:4422145, PMID:19754877
acts_upstream_of_or_within GO:0045944 positive regulation of transcription by RNA polymerase II MGI:4422145, PMID:19754877
located_in GO:0005634 nucleus MGI:5607133, PMID:17643418
located_in GO:0005634 nucleus MGI:5607132, PMID:19028714
located_in GO:0005634 nucleus MGI:4422145, PMID:19754877
PR:Q61699-1
mHSPH1/iso:HSP105-alpha
acts_upstream_of_or_within GO:1903753 negative regulation of p38MAPK cascade MGI:3822965, PMID:18681888
acts_upstream_of_or_within GO:1903751 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide MGI:3822965, PMID:18681888
acts_upstream_of_or_within GO:1903748 negative regulation of establishment of protein localization to mitochondrion MGI:3688933, PMID:16857185
acts_upstream_of_or_within GO:2001234 negative regulation of apoptotic signaling pathway MGI:3688933, PMID:16857185
located_in GO:0005737 cytoplasm MGI:5607133, PMID:17643418
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:Q61699-2 mHSPH1/iso:HSP105-beta

MGI:5607133, PMID:17643418
PR:Q61699-2 mHSPH1/iso:HSP105-beta

MGI:5607132, PMID:19028714
PR:Q61699-2 mHSPH1/iso:HSP105-beta

MGI:4422145, PMID:19754877
GO:0005737 cytoplasm PR:Q61699-1 mHSPH1/iso:HSP105-alpha

MGI:5607133, PMID:17643418

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