PRO Entry Report - PR:000003745

Protein Forms Annotations

Ontology Information

PRO ID

PR:000003745 Show OBO stanza / PAF

PRO name

double-stranded RNA-specific adenosine deaminase

Synonyms

PRO-short-label:	EXACT:	ADAR
Gene-based:	RELATED:	ADAR1 \| DSRAD \| G1P1 \| IFI4
Other:	EXACT:	136 kDa double-stranded RNA-binding protein \| DRADA \| IFI-4 \| K88DSRBP \| RNA adenosine deaminase 1 \| interferon-inducible protein 4
	BROAD:	p136

Definition

A protein that is a translation product of the human ADAR gene or a 1:1 ortholog thereof. [PRO:DNx]

PRO Category

gene

Parent

Terms by PRO Category

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Term Hierarchy Visualization

DAG

OLS

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:Q99MU3-4 mADAR/iso:4	enables	GO:0003726 double-stranded RNA adenosine deaminase activity	MGI:5515381, PMID:12954622
PR:Q99MU3-1 mADAR/iso:1	acts_upstream_of_or_within	GO:0045071 negative regulation of viral genome replication	MGI:4939544, PMID:21173229
	acts_upstream_of_or_within	GO:0001701 in utero embryonic development	MGI:4939544, PMID:21173229
	acts_upstream_of_or_within	GO:0051607 defense response to virus	MGI:4939544, PMID:21173229
	enables	GO:0003726 double-stranded RNA adenosine deaminase activity	MGI:5515381, PMID:12954622
	located_in	GO:0005737 cytoplasm	MGI:5515381, PMID:12954622
PR:Q99MU3-2 mADAR/iso:2	enables	GO:0003726 double-stranded RNA adenosine deaminase activity	MGI:5515381, PMID:12954622
PR:Q99MU3-2 mADAR/iso:2	located_in	GO:0005737 cytoplasm	MGI:5515381, PMID:12954622
PR:Q99MU3-3 mADAR/iso:3	enables	GO:0003726 double-stranded RNA adenosine deaminase activity	MGI:5515381, PMID:12954622
PR:Q99MU3-3 mADAR/iso:3	located_in	GO:0005730 nucleolus	MGI:5515381, PMID:12954622

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