back to PRO homepage
  Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology Report - DNMT1

PR:000006606 - http://purl.obolibrary.org/obo/PR_000006606
Ontology Information
PRO ID PR:000006606 Show OBO stanza / PAF
PRO name DNA (cytosine-5)-methyltransferase 1
Synonyms
PRO-short-label: EXACT: DNMT1
Gene-based: RELATED: AIM | CXXC9 | DNMT | Met1 | Uim
Other: EXACT: CXXC-type zinc finger protein 9 | DNA MTase HsaI | DNA MTase MmuI | DNA methyltransferase HsaI | DNA methyltransferase MmuI | Dnmt1 | M.HsaI | M.MmuI | MCMT | met-1
Definition A protein that is a translation product of the human DNMT1 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 4
sequence 0 organism-sequence 14
modification 0 organism-modification 3
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

DNMT1 forms found in complexes
DNMT1 Component Complexes
PR:000037504 hDNMT1/UnPhos:1 PR:000037517 DNMT1:PCNA:UHRF1 complex (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000037506
hDNMT1/Phos:2
Ser-127/Ser-143, MOD:00046
enables GO:0005515 protein binding decreased relative to PR:000037504 hDNMT1/UnPhos:1 with PR:P12004 hPCNA PMID:20613874
enables GO:0005515 protein binding decreased relative to PR:000037504 hDNMT1/UnPhos:1 with PR:Q96T88 hUHRF1 PMID:20613874
PR:000037505
hDNMT1/Phos:1
Ser-127, MOD:00046
enables GO:0005515 protein binding decreased relative to PR:000037504 hDNMT1/UnPhos:1 with PR:Q96T88 hUHRF1 PMID:20613874
enables GO:0005515 protein binding decreased relative to PR:000037504 hDNMT1/UnPhos:1 with PR:P12004 hPCNA PMID:20613874
PR:000037504
hDNMT1/UnPhos:1
Ser-127/Ser-143, PR:000026291
enables GO:0005515 protein binding with PR:P12004 hPCNA PMID:20613874
enables GO:0005515 protein binding with PR:Q96T88 hUHRF1 PMID:20613874
PR:000037517
DNMT1:PCNA:UHRF1 complex (human)
associated_with_disease_suppression DOID:162 cancer PMID:20613874

top