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Protein Ontology Report - SLC12A1

PR:000014924 - http://purl.obolibrary.org/obo/PR_000014924
Ontology Information
PRO ID PR:000014924 Show OBO stanza / PAF
PRO name solute carrier family 12 member 1
Synonyms
PRO-short-label: EXACT: SLC12A1
Gene-based: RELATED: NKCC2
Other: EXACT: BSC1 | bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 | kidney-specific Na-K-Cl symporter
Definition A protein that is a translation product of the human SLC12A1 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 0 organism-sequence 7
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P55014-1
mSlc12a1/iso:A
acts_upstream_of_or_within GO:0070886 positive regulation of calcineurin-NFAT signaling cascade MGI:4947009, PMID:21228109
acts_upstream_of_or_within GO:0071475 cellular hyperosmotic salinity response MGI:4947009, PMID:21228109
PR:P55014-4
mSlc12a1/iso:F
enables GO:0008511 sodium:potassium:chloride symporter activity MGI:5538439, PMID:24133122
enables GO:0005515 protein binding with PR:000044370|PR:G1JLS7|PR:Q9Z1W9-1 MGI:5538439, PMID:24133122

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