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Protein Ontology Report - hCDKN1B/iso:1/Phos:2

PR:000025750 - http://purl.obolibrary.org/obo/PR_000025750
Ontology Information
PRO ID PR:000025750 Show OBO stanza / PAF
PRO name cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human)
Synonyms
PRO-short-label: hCDKN1B/iso:1/Phos:2
PRO-proteoform-std: UniProtKB:P46527-1, Tyr-88, MOD:00048
Definition A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 in human. Phosphorylation at this site promotes subsequent Cdk2-mediated phosphorylation at Thr-187. UniProtKB:P46527-1, Tyr-88, MOD:00048. [PMID:17254966, PRO:JAN]
PRO Category organism-modification
Parent PR:000025749 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000025750
hCDKN1B/iso:1/Phos:2
Tyr-88, MOD:00048
capable_of GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity decreased relative to PR:000045370 hCDKN1B/iso:1/UnPhos:2 PMID:17254966
capable_of GO:0044877 protein-containing complex binding with PR:000026741 cyclin D1:Cdk4 (human) PMID:17254966
capable_of GO:0005515 protein binding with PR:P24864 hCCNE1 PMID:17254966
capable_of GO:0005515 protein binding with PR:P24385 hCCND1 PMID:17254966
capable_of GO:0005515 protein binding with PR:P20248 hCCNA2 PMID:17254966
participates_in GO:0051318 G1 phase PMID:17254966
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0051318 G1 phase PR:000025750 hCDKN1B/iso:1/Phos:2
Tyr-88, MOD:00048
PMID:17254966

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