| PRO ID |
PR:000025751
Show OBO stanza
|
| PRO name |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 |
| Synonyms |
| PRO-short-label: |
EXACT: |
CDKN1B/iso:1/Phos:3 |
| Other: |
RELATED: |
p27 phosphorylated form |
|
| Definition |
A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form in which the phosphorylation occurs at a conserved Tyr residue that is major phosphoacceptor site in the Cdk-binding domain, and phosphorylated by CDK2 on a Thr residue in the C-terminal region. Phosphorylation by CDK2 promotes degradation by the SCF-Skp2 ubiquitin-proteasome pathway. Example: UniProtKB:P46527-1, Tyr-88, MOD:00048, Thr-187, MOD:00047.
[PMID:17254966, PRO:CNA, PRO:DAN]
|
| PRO Category |
modification |
| Parent |
PR:000003093 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form |
| Term Hierarchy Visualization |
 DAG
 OLS
Cytoscape
|
