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Protein Ontology Report - hEIF3F/iso:1/Phos:1

PR:000025800 - http://purl.obolibrary.org/obo/PR_000025800
Ontology Information
PRO ID PR:000025800 Show OBO stanza / PAF
PRO name eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated 1 (human)
Synonyms
PRO-short-label: EXACT: hEIF3F/iso:1/Phos:1
PRO-proteoform-std: EXACT: UniProtKB:O00303-1, Ser-46, MOD:00046|Thr-119, MOD:00047
Definition A eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated form in human in which the phosphorylation occurs by CDK11B isoform SV1 (ALpha 2-1). UniProtKB:O00303-1, Ser-46, MOD:00046, Thr-119, MOD:00047. [PMID:19245811, PRO:JAN]
PRO Category organism-modification
Parent PR:000025799 eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated form
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000025800
hEIF3F/iso:1/Phos:1
Ser-46, MOD:00046|Thr-119, MOD:00047
capable_of GO:0031369 translation initiation factor binding increased relative to PR:000025839 hEIF3F/iso:1/UnMod with PR:P55884 hEIF3B PMID:19245811
part_of GO:0005852 eukaryotic translation initiation factor 3 complex PMID:19245811
participates_in GO:0043065 positive regulation of apoptotic process PMID:19245811
participates_in GO:0017148 negative regulation of translation PMID:19245811
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0043065 positive regulation of apoptotic process PR:000025800 hEIF3F/iso:1/Phos:1
Ser-46, MOD:00046|Thr-119, MOD:00047
PMID:19245811
GO:0017148 negative regulation of translation PR:000025800 hEIF3F/iso:1/Phos:1
Ser-46, MOD:00046|Thr-119, MOD:00047
PMID:19245811

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