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Protein Ontology Report - hSMAD2/iso:Short/Phos:1

PR:000025938 -
Ontology Information
PRO ID PR:000025938 Show OBO stanza / PAF / GPI
PRO name smad2 isoform Short phosphorylated 1 (human)
PRO-short-label: EXACT: hSMAD2/iso:Short/Phos:1
PRO-proteoform-std: EXACT: UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046
Definition A smad2 isoform Short phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046. [PRO:CNA]
Comment Kinase=("TGFBR1"; PR:000025963; Ser-435/Ser-437).
PRO Category organism-modification
Parent PR:000000656 smad2 isoform Short phosphorylated 1
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hSMAD2/iso:Short/Phos:1 forms found in complexes
hSMAD2/iso:Short/Phos:1 Component Complexes
PR:000025938 hSMAD2/iso:Short/Phos:1 PR:000025940 smad2-smad4 protein complex 2 (human)

Functional Annotation
PRO Term GO Annotation Evidence
Ser-435/Ser-437, MOD:00046
acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:9873005
enables GO:0003712 transcription coregulator activity PMID:14701940, PMID:9873005
enables GO:0003677 DNA binding PMID:14701940, PMID:9873005
enables GO:0003700 DNA-binding transcription factor activity PMID:9873005