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Protein Ontology Report - mSMAD2/iso:Long/Phos:1

PR:000025942 - http://purl.obolibrary.org/obo/PR_000025942
Ontology Information
PRO ID PR:000025942 Show OBO stanza / PAF
PRO name smad2 isoform Long phosphorylated 1 (mouse)
Synonyms
PRO-short-label: EXACT: mSMAD2/iso:Long/Phos:1
PRO-proteoform-std: EXACT: UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046
Definition A smad2 isoform Long phosphorylated 1 in mouse. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046. [PMID:8980228, PMID:9346966]
Comment Kinase=("TGFBR1"; PR:000025976; Ser-465/Ser-467).
PRO Category organism-modification
Parent PR:000000650 smad2 isoform Long phosphorylated 1
Taxon NCBITaxon:10090 Mus musculus
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mSMAD2/iso:Long/Phos:1 forms found in complexes
mSMAD2/iso:Long/Phos:1 Component Complexes
PR:000025942 mSMAD2/iso:Long/Phos:1 PR:000025944 smad2-smad4 protein complex 1 (mouse)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000025942
mSMAD2/iso:Long/Phos:1
Ser-465/Ser-467, MOD:00046
capable_of GO:0003713 transcription coactivator activity PMID:15282343
capable_of GO:0046332 SMAD binding with PR:P97471 mSMAD4 PMID:11043574
located_in GO:0005634 nucleus PMID:11557747
participates_in GO:0007165 signal transduction PMID:11262418
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11262418
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007179 transforming growth factor beta receptor signaling pathway PR:000025942 mSMAD2/iso:Long/Phos:1
Ser-465/Ser-467, MOD:00046
PMID:11262418
GO:0007165 signal transduction PR:000025942 mSMAD2/iso:Long/Phos:1
Ser-465/Ser-467, MOD:00046
PMID:11262418
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000025942 mSMAD2/iso:Long/Phos:1
Ser-465/Ser-467, MOD:00046
PMID:11557747

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