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Protein Ontology Report - serine palmitoyltransferase complex 5 (human)

PR:000026153 - http://purl.obolibrary.org/obo/PR_000026153
Ontology Information
PRO ID PR:000026153 Show OBO stanza / PAF
PRO name serine palmitoyltransferase complex 5 (human)
Definition A serine palmitoyltransferase complex whose components are the same as serine palmitoyltransferase complex core 1 (serine palmitoyltransferase 1 and serine palmitoyltransferase 2) plus the accessory small subunit A. These components are encoded in the genome of human. The biological unit of SPT complex may consist of multiple copies of the core 1 and/or core 2 in combination with additional subunits. [PMID:17331073, PMID:19648650, PRO:CNA]
Comment This entity is disposed to have the enzymatic activity described by EC:2.3.1.50.
PRO Category organism-complex
Parent GO:0017059 serine C-palmitoyltransferase complex
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000026153 PR:Q969W0 serine palmitoyltransferase small subunit A (human) hSPTSSA A serine palmitoyltransferase small subunit A that is encoded in the genome of human. [PMID:19416851, PRO:CNA]
PR:O15270 serine palmitoyltransferase 2 (human) hSPTLC2 A serine palmitoyltransferase 2 that is encoded in the genome of human. [PRO:CNA]
PR:O15269 serine palmitoyltransferase 1 (human) hSPTLC1 A serine palmitoyltransferase 1 that is encoded in the genome of human. [PRO:CNA]


Functional Annotation
PRO Term GO Annotation Evidence
PR:000026153
serine palmitoyltransferase complex 5 (human)
enables GO:0004758 serine C-palmitoyltransferase activity increased relative to PR:000026144 serine palmitoyltransferase complex core 1 (human) PMID:19416851

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