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Protein Ontology Report - MYD88s:TIRAP:activated TLR4 receptor (mouse)

PR:000027174 - http://purl.obolibrary.org/obo/PR_000027174
Ontology Information
PRO ID PR:000027174 Show OBO stanza / PAF / GPI
PRO name MYD88s:TIRAP:activated TLR4 receptor (mouse)
Synonyms
Other: EXACT: MYD88s:Mal:activated TLR4 receptor (mouse) | TLR4MD2LPSditms
Definition A MYD88:TIRAP:activated TLR4 receptor whose components are encoded in the genome of mouse. This complex contains the short isoform of MYD88. [PMID:12538665, TLR:AMM]
Comment Requested by=TLR.
PRO Category organism-complex
Parent PR:000025784 MYD88:TIRAP:activated TLR4 receptor
Taxon NCBITaxon:10090 Mus musculus
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000027174 PR:P22366-2 myeloid differentiation primary response protein MyD88 isoform 2 (mouse) mMYD88/iso:2 A myeloid differentiation primary response protein MyD88 isoform 2 that is encoded in the genome of mouse. [PMID:11909531, PRO:CNA] 2
PR:Q99JY1 Toll/interleukin-1 receptor domain-containing adapter protein (mouse) mTIRAP A Toll/interleukin-1 receptor domain-containing adapter protein that is encoded in the genome of mouse. [OMA:Q99JY1, PRO:CNA] 2
PR:000027171 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse) mLY96/iso:1/SigPep-/NGlyco:1 A lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form in mouse that has been N-glycosylated on Asn residues at positions 26, 114, and 150 of the amino acid sequence represented by UniProtKB:Q9JHF9-1. UniProtKB:Q9JHF9-1, 19-160, Asn-26/Asn-114/Asn-150, MOD:00160. [PMID:17803912, PRO:CNA] 2
PR:000027172 Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (mouse) mTLR4/iso:1/SigPep-/NGlyco:1 A Toll-like receptor 4 isoform 1, signal peptide removed form in mouse that has been N-glycosylated on Asn residues at positions 34, 75, 172, 204, 237, 307, 492, 524 and 572 of the amino acid sequence represented by UniProtKB:Q9QUK6-1. UniProtKB:Q9QUK6-1, 26-835, Asn-34/Asn-75/Asn-172/Asn-204/Asn-237/Asn-307/Asn-492/Asn-524/Asn-572, MOD:00160. [PMID:17803912, PRO:CNA] 2
CHEBI:16412 lipopolysaccharide lipopolysaccharide Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). [fake:1] 2


Functional Annotation
PRO Term GO Annotation Evidence
PR:000027174
MYD88s:TIRAP:activated TLR4 receptor (mouse)
acts_upstream_of_or_within GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway PMID:12538665

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