PRO ID |
PR:000027830
Show OBO stanza
|
PRO name |
cellular tumor antigen p53 isoform 1 phosphorylated 8 |
Synonyms |
PRO-short-label: |
EXACT: |
TP53/iso:1/Phos:8 |
|
Definition |
A cellular tumor antigen p53 isoform 1 that has been phosphorylated at two Ser residues, one located in the DNA-binding domain and the other within the nuclear localization signal of the C-terminus of p53. Phosphorylation at Ser-215 hinders DNA binding and transactivation activity of p53. Example: UniProtKB:P04637-1, Ser-215/Ser-315, MOD:00046.
[PMID:15469940, PRO:PD]
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PRO Category |
modification |
Parent |
PR:000003036 cellular tumor antigen p53 isoform 1 |
Term Hierarchy Visualization |
DAG
OLS
Cytoscape
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