PRO Entry Report - PR:000027942

Protein Ontology Report - CDK9:cyclin-T1

PR:000027942 - http://purl.obolibrary.org/obo/PR_000027942

Complex Forms Complex Subunits Annotations

Ontology Information

PRO ID

PR:000027942 Show OBO stanza / PAF

PRO name

CDK9:cyclin-T1

Synonyms

Other:	EXACT:	CDK9-cyclin T1
	RELATED:	dimeric P-TEFb

Definition

A dimeric positive transcription elongation factor complex b that contains cyclin-T1 and acetylated cyclin-dependent protein kinase catalytic (CDCK9) subunit. [PMID:17452463, PRO:CNA]

PRO Category

complex

Parent

GO:0070691 P-TEFb complex

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
complex	1	organism-complex	1

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Complex Forms

PRO ID & Category Annotation Subunits	Name	Short Label	Definition & Comment

Complex Subunits

Complex	PRO ID	Name	Short Label	Definition	Number in Complex
PR:000027942	PR:000027933	cyclin-dependent kinase 9 isoform 1 acetylated 1	CDK9/iso:1/Ac:1	A cyclin-dependent kinase 9 isoform 1 that has been acetylated in the first Lys residue of the conserved sequence Kx(1-2)A[LM]KKV. Example: UniProtKB:P50750-1, Lys-44, MOD:00064. [KAT:P50750, PMID:17452463]	1
PR:000027942	PR:000005139	cyclin-T1	CCNT1	A cyclin-related protein that is a translation product of the human CCNT1 gene or a 1:1 ortholog thereof. [PRO:DNx]	1
PR:000027943	PR:O60563	cyclin-T1 (human)	hCCNT1	A cyclin-T1 that is encoded in the genome of human. [PRO:CNA]	1
PR:000027943	PR:000027934	cyclin-dependent kinase 9 isoform 1 acetylated 1 (human)	hCDK9/iso:1/Ac:1	A cyclin-dependent kinase 9 isoform 1 acetylated 1 in human. UniProtKB:P50750-1, Lys-44, MOD:00064. [KAT:P50750, PMID:17452463]	1

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000027943 CDK9:cyclin-T1 (human)	acts_upstream_of_or_within	GO:0006468 protein phosphorylation	PMID:17452463
	acts_upstream_of_or_within	GO:0006354 DNA-templated transcription elongation	PMID:17452463
	enables	GO:0097472 cyclin-dependent protein kinase activity	PMID:17452463
	located_in	GO:0005634 nucleus	PMID:17452463

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005634 nucleus	PR:000027943 CDK9:cyclin-T1 (human)	PMID:17452463

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