Protein Ontology Report - cyclin B:Cdk1 complex PR:000029190 - http://purl.obolibrary.org/obo/PR_000029190

Ontology Information
PRO ID	PR:000029190 Show OBO stanza
PRO name	cyclin B:Cdk1 complex
Synonyms	Other: EXACT: cyclin B:Cdc2 complex
Definition	A cyclin-dependent protein kinase holoenzyme complex that has a cyclin B regulatory subunit and a Cdk1 kinase subunit. [PRO:CNA]
PRO Category	complex
Parent	GO:0000307 cyclin-dependent protein kinase holoenzyme complex
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Independent Organism-Specific Category Number of Terms Category Number of Terms complex 8 organism-complex 8
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Complex Forms Display Category: All All complex organism-complex
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits

Complex PRO ID Name Short Label Definition Number in Complex PR:000027146 PR:P14635 G2/mitotic-specific cyclin-B1 (human) hCCNB1 A G2/mitotic-specific cyclin-B1 that is encoded in the genome of human. [PRO:DAN] 1 PR:000027124 cyclin-dependent kinase 1 isoform 1 phosphorylated 4 (human) hCDK1/iso:1/Phos:4 A cyclin-dependent kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047|Tyr-15, MOD:00048. [PRO:DAN, Reactome:R-HSA-170071, Reactome:R-HSA-170074] 1 PR:000027147 PR:000026211 cyclin-dependent kinase 1 isoform 1 phosphorylated 2 (human) hCDK1/iso:1/Phos:2 A cyclin-dependent kinase 1 isoform 1 phosphorylated 2 in human. UniProtKB:P06493-1, Thr-161, MOD:00047. [PRO:CNx, Reactome:R-HSA-157415, Reactome:R-HSA-170066] 1 PR:000027130 G2/mitotic-specific cyclin-B1 phosphorylated 1 (human) hCCNB1/Phos:1 A G2/mitotic-specific cyclin-B1 phosphorylated 1 in human. Example: UniProtKB:P14635-1, Ser-126/Ser-128/Ser-133/Ser-147, MOD:00046. [PRO:DAN, Reactome:R-HSA-170049, Reactome:R-HSA-170058] 1 PR:000027144 PR:P14635 G2/mitotic-specific cyclin-B1 (human) hCCNB1 A G2/mitotic-specific cyclin-B1 that is encoded in the genome of human. [PRO:DAN] 1 PR:000026211 cyclin-dependent kinase 1 isoform 1 phosphorylated 2 (human) hCDK1/iso:1/Phos:2 A cyclin-dependent kinase 1 isoform 1 phosphorylated 2 in human. UniProtKB:P06493-1, Thr-161, MOD:00047. [PRO:CNx, Reactome:R-HSA-157415, Reactome:R-HSA-170066] 1 PR:000027145 PR:P14635 G2/mitotic-specific cyclin-B1 (human) hCCNB1 A G2/mitotic-specific cyclin-B1 that is encoded in the genome of human. [PRO:DAN] 1 PR:000027123 cyclin-dependent kinase 1 isoform 1 phosphorylated 3 (human) hCDK1/iso:1/Phos:3 A cyclin-dependent kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047. [PRO:DAN, Reactome:R-HSA-170078, Reactome:R-HSA-170291] 1 PR:000027143 PR:P14635 G2/mitotic-specific cyclin-B1 (human) hCCNB1 A G2/mitotic-specific cyclin-B1 that is encoded in the genome of human. [PRO:DAN] 1 PR:000026181 cyclin-dependent kinase 1 isoform 1 phosphorylated 1 (human) hCDK1/iso:1/Phos:1 A cyclin-dependent kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P06493-1, Thr-14, MOD:00047. [PRO:CNx, Reactome:R-HSA-170045, Reactome:R-HSA-170064] 1 PR:000027148 PR:O95067 G2/mitotic-specific cyclin-B2 (human) hCCNB2 A G2/mitotic-specific cyclin-B2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:O95067] 1 PR:000026211 cyclin-dependent kinase 1 isoform 1 phosphorylated 2 (human) hCDK1/iso:1/Phos:2 A cyclin-dependent kinase 1 isoform 1 phosphorylated 2 in human. UniProtKB:P06493-1, Thr-161, MOD:00047. [PRO:CNx, Reactome:R-HSA-157415, Reactome:R-HSA-170066] 1 PR:000027149 PR:O95067 G2/mitotic-specific cyclin-B2 (human) hCCNB2 A G2/mitotic-specific cyclin-B2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:O95067] 1 PR:000027123 cyclin-dependent kinase 1 isoform 1 phosphorylated 3 (human) hCDK1/iso:1/Phos:3 A cyclin-dependent kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047. [PRO:DAN, Reactome:R-HSA-170078, Reactome:R-HSA-170291] 1 PR:000027137 PR:000026182 cyclin-dependent kinase 1 isoform 1 phosphorylated 2 CDK1/iso:1/Phos:2 A cyclin-dependent kinase 1 isoform 1 that has been post-translationally modified to include a phosphorylated Thr residue at the position equivalent to Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-161, MOD:00047. [PRO:CNx] 1 PR:000027129 G2/mitotic-specific cyclin-B1 phosphorylated 1 CCNB1/Phos:1 A G2/mitotic-specific cyclin-B1 phosphorylated form that includes phosphorylation at positions equivalent to Ser-126, Ser-128, Ser-133, and Ser-147 of the amino acid sequence represented by UniProtKB:P14635-1. Example: UniProtKB:P14635-1, Ser-126/Ser-128/Ser-133/Ser-147, MOD:00046. [PRO:DAN] 1 PR:000027136 PR:000027122 cyclin-dependent kinase 1 isoform 1 phosphorylated 4 CDK1/iso:1/Phos:4 A cyclin-dependent kinase 1 isoform 1 that has been phosphorylated at positions equivalent to Thr-14, Tyr-15, and Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047|Tyr-15, MOD:00048. [PRO:DAN, Reactome:R-HSA-170071, Reactome:R-HSA-170074] 1 PR:000005116 G2/mitotic-specific cyclin-B1 CCNB1 A G2/mitotic-specific cyclin-B that is a translation product of the human CCNB1 gene or a 1:1 ortholog thereof. [PRO:CNA] 1 PR:000027135 PR:000027121 cyclin-dependent kinase 1 isoform 1 phosphorylated 3 CDK1/iso:1/Phos:3 A cyclin-dependent kinase 1 isoform 1 that has been phosphorylated at positions equivalent to Thr-14 and Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047. [PRO:DAN, Reactome:R-HSA-170078, Reactome:R-HSA-170291] 1 PR:000005116 G2/mitotic-specific cyclin-B1 CCNB1 A G2/mitotic-specific cyclin-B that is a translation product of the human CCNB1 gene or a 1:1 ortholog thereof. [PRO:CNA] 1 PR:000027134 PR:000026182 cyclin-dependent kinase 1 isoform 1 phosphorylated 2 CDK1/iso:1/Phos:2 A cyclin-dependent kinase 1 isoform 1 that has been post-translationally modified to include a phosphorylated Thr residue at the position equivalent to Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-161, MOD:00047. [PRO:CNx] 1 PR:000005116 G2/mitotic-specific cyclin-B1 CCNB1 A G2/mitotic-specific cyclin-B that is a translation product of the human CCNB1 gene or a 1:1 ortholog thereof. [PRO:CNA] 1 PR:000027133 PR:000026180 cyclin-dependent kinase 1 isoform 1 phosphorylated 1 CDK1/iso:1/Phos:1 A cyclin-dependent kinase 1 isoform 1 that has been phosphorylated on a Thr residue within the N-terminal nucleotide binding region. This modification inactivates the kinase. Example: UniProtKB:P06493-1, Thr-14, MOD:00047. [PRO:CNx, Reactome:R-HSA-170045, Reactome:R-HSA-170064] 1 PR:000005116 G2/mitotic-specific cyclin-B1 CCNB1 A G2/mitotic-specific cyclin-B that is a translation product of the human CCNB1 gene or a 1:1 ortholog thereof. [PRO:CNA] 1 PR:000029190 PR:000027125 cyclin-dependent kinase 1 phosphorylated form CDK1/PhosRes+ A cyclin-dependent kinase 1 that includes at least one phosphorylated residue. [PRO:DAN] 1 PR:000029192 G2/mitotic-specific cyclin-B fam:CCNB A cyclin-related protein that is a translation product of the human CCNB1, CCNB2, or CCNB3 genes, or 1:1 orthologs thereof. [PRO:CNA, Wikipedia:Cyclin] 1 PR:000027139 PR:000027121 cyclin-dependent kinase 1 isoform 1 phosphorylated 3 CDK1/iso:1/Phos:3 A cyclin-dependent kinase 1 isoform 1 that has been phosphorylated at positions equivalent to Thr-14 and Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047. [PRO:DAN, Reactome:R-HSA-170078, Reactome:R-HSA-170291] 1 PR:000005118 G2/mitotic-specific cyclin-B2 CCNB2 A G2/mitotic-specific cyclin-B that is a translation product of the human CCNB2 gene or a 1:1 ortholog thereof. [PRO:CNA] 1 PR:000027138 PR:000026182 cyclin-dependent kinase 1 isoform 1 phosphorylated 2 CDK1/iso:1/Phos:2 A cyclin-dependent kinase 1 isoform 1 that has been post-translationally modified to include a phosphorylated Thr residue at the position equivalent to Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-161, MOD:00047. [PRO:CNx] 1 PR:000005118 G2/mitotic-specific cyclin-B2 CCNB2 A G2/mitotic-specific cyclin-B that is a translation product of the human CCNB2 gene or a 1:1 ortholog thereof. [PRO:CNA] 1 PR:000037318 PR:000036301 cyclin-dependent kinase 1 (Schizosaccharomyces pombe) Spom-cdc2 A fungal-type cyclin-dependent kinase 1 that is encoded in the genome of Schizosaccharomyces pombe. [PRO:DAN] PR:000036302 G2/mitotic-specific cyclin cdc13 (Schizosaccharomyces pombe) Spom-cdc13 A G2/mitotic-specific cyclin cdc13 that is encoded in the genome of Schizosaccharomyces pombe. [PRO:DAN]

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