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Protein Ontology Report - hKCNN3/var:1

PR:000029956 - http://purl.obolibrary.org/obo/PR_000029956
Ontology Information
PRO ID PR:000029956 Show OBO stanza / PAF
PRO name small conductance calcium-activated potassium channel protein 3 sequence variant 1 (human)
Synonyms
PRO-short-label: EXACT: hKCNN3/var:1
Other: EXACT: SKCa3Delta (human)
Definition A small conductance calcium-activated potassium channel protein 3 (human) that has a C-terminal truncation due to frameshift and premature stop, such that the sequence is equivalent to UniProtKB:Q9UGI6-1, 1-283, plus the residues TML. The truncated protein lacks the transmembrane and the calmodulin binding domains. However, it conserves the two glutamine rich domains. [PMID:11395478, PRO:DAN]
Comment Note: The referenced paper shows a sequence that is itself based on a variant of the canonical sequence. The sequence of the variant is EMBL:AAC26099.
PRO Category organism-sequence
Parent PR:Q9UGI6 small conductance calcium-activated potassium channel protein 3 (human)
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000029956
hKCNN3/var:1
capable_of NOT GO:0015269 calcium-activated potassium channel activity PMID:11395478
located_in GO:0005634 nucleus PMID:11395478
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000029956 hKCNN3/var:1

PMID:11395478

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