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Protein Ontology Report - hCD14/iso:1/Clv:2/anchored

PR:000035702 -
Ontology Information
PRO ID PR:000035702 Show OBO stanza / PAF / GPI
PRO name CD14 molecule isoform 1 cleaved 2 GPI-anchored form (human)
PRO-short-label: EXACT: hCD14/iso:1/Clv:2/anchored
PRO-proteoform-std: EXACT: UniProtKB:P08571-1, 20-345, Asn-345, MOD:00167
PRO-proteoform-ftid: EXACT: PRO_0000020885, Asn-345, MOD:00167
Other: EXACT: GPI-N345-CD14 (human) | GPI-anchored form of CD14 (human)
Definition A CD14 molecule isoform 1 cleaved 2 GPI-anchored form in human. UniProtKB:P08571-1, 20-345, Asn-345, MOD:00167. [Reactome:R-HSA-166033, Reactome:R-HSA-2201284]
PRO Category organism-modification
Parent PR:000002149 CD14 molecule isoform 1 cleaved 2 GPI-anchored form
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hCD14/iso:1/Clv:2/anchored forms found in complexes
hCD14/iso:1/Clv:2/anchored Component Complexes
PR:000035702 hCD14/iso:1/Clv:2/anchored PR:000027208 ticam1:ticam2:activated TLR4 complex (human)
PR:000035702 hCD14/iso:1/Clv:2/anchored PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000035702 hCD14/iso:1/Clv:2/anchored PR:000028680 traf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035702 hCD14/iso:1/Clv:2/anchored PR:000036022 traf3:ticam1:ticam2:activated TLR4 complex (human)
PR:000035702 hCD14/iso:1/Clv:2/anchored PR:000037464 LPS:GPI-anchored CD14 complex (human)
PR:000035702 hCD14/iso:1/Clv:2/anchored PR:000025773 lipopolysaccharide receptor complex 3 (human)

Functional Annotation
PRO Term GO Annotation Evidence
Asn-345, MOD:00167
acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894
located_in GO:0005886 plasma membrane PMID:2779588, PMID:3385210, PMID:9665271
located_in GO:0005886 plasma membrane Reactome:REACT_7740
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005886 plasma membrane PR:000035702 hCD14/iso:1/Clv:2/anchored
Asn-345, MOD:00167
PMID:2779588, PMID:3385210, PMID:9665271
PR:000035702 hCD14/iso:1/Clv:2/anchored
Asn-345, MOD:00167