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Protein Ontology Report - tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex

PR:000036096 - http://purl.obolibrary.org/obo/PR_000036096
Ontology Information
PRO ID PR:000036096 Show OBO stanza
PRO name tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex
Synonyms
Other: BROAD: K63-poly-Ub-tank:TRAF3:TRIF:TRAM:activated TLR4
Definition A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), TICAM2, TICAM1, TRAF3, TBK1 and TANK linked to Lys-63 polyubiquitin. [TLR:AMM]
Comment Requested by=TLR.
PRO Category complex
Parent GO:0032991 protein-containing complex
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
complex 1 organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000036097 PR:000027171 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse) mLY96/iso:1/SigPep-/NGlyco:1 A lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form in mouse that has been N-glycosylated on Asn residues at positions 26, 114, and 150 of the amino acid sequence represented by UniProtKB:Q9JHF9-1. UniProtKB:Q9JHF9-1, 19-160, Asn-26/Asn-114/Asn-150, MOD:00160. [PMID:17803912, PRO:CNA]
PR:000027172 Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (mouse) mTLR4/iso:1/SigPep-/NGlyco:1 A Toll-like receptor 4 isoform 1, signal peptide removed form in mouse that has been N-glycosylated on Asn residues at positions 34, 75, 172, 204, 237, 307, 492, 524 and 572 of the amino acid sequence represented by UniProtKB:Q9QUK6-1. UniProtKB:Q9QUK6-1, 26-835, Asn-34/Asn-75/Asn-172/Asn-204/Asn-237/Asn-307/Asn-492/Asn-524/Asn-572, MOD:00160. [PMID:17803912, PRO:CNA]
PR:000036091 TRAF family member-associated NF-kappa-B activator isoform 1 K63-polyubiquitinated form (mouse) mTANK/iso:1/K63polyUbiq+ A TRAF family member-associated NF-kappa-B activator isoform 1 K63-polyubiquitinated form in mouse. UniProtKB:P70347-1, PR:000044772. [TLR:AMM]
CHEBI:16412 lipopolysaccharide lipopolysaccharide Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). [fake:1]
PR:Q9WUN2 serine/threonine-protein kinase TBK1 (mouse) mTBK1 A serine/threonine-protein kinase TBK1 that is encoded in the genome of mouse. [OMA:Q9WUN2, PRO:CNA]
PR:Q60803 TNF receptor-associated factor 3 (mouse) mTRAF3 A TNF receptor-associated factor 3 that is encoded in the genome of mouse. [OMA:Q60803, PRO:CNA]
PR:Q8BJQ4 TIR domain-containing adapter molecule 2 (mouse) mTICAM2 A TIR domain-containing adapter molecule 2 that is encoded in the genome of mouse. [OMA:Q8BJQ4, PRO:CNA]
PR:Q80UF7 TIR domain-containing adapter molecule 1 (mouse) mTICAM1 A TIR domain-containing adapter molecule 1 that is encoded in the genome of mouse. [OMA:Q80UF7, PRO:CNA]


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