PRO Entry Report - PR:000036643

Protein Ontology Report - hRAF1/iso:1/Phos:2

PR:000036643 - http://purl.obolibrary.org/obo/PR_000036643

Protein Forms Annotations

Ontology Information

PRO ID

PR:000036643 Show OBO stanza / PAF / GPI

PRO name

RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 (human)

Synonyms

PRO-short-label:	EXACT:	hRAF1/iso:1/Phos:2
PRO-proteoform-std:	EXACT:	UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046

Definition

A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 in human. UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046. [PMID:15849194, PRO:JAN]

PRO Category

organism-modification

Parent

PR:000003250 RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2

Taxon

NCBITaxon:9606 Homo sapiens

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000036643 hRAF1/iso:1/Phos:2 Ser-338/Ser-339, MOD:00046	acts_upstream_of_or_within	GO:0043066 negative regulation of apoptotic process	PMID:15849194
	enables	GO:0005515 protein binding with PR:P10415 hBCL2	PMID:15849194
	enables	GO:0004674 protein serine/threonine kinase activity	PMID:15849194
	located_in	GO:0005741 mitochondrial outer membrane	PMID:15849194

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005741 mitochondrial outer membrane	PR:000036643 hRAF1/iso:1/Phos:2 Ser-338/Ser-339, MOD:00046	PMID:15849194

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