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Protein Ontology Report - DenV-E

PR:000036822 - http://purl.obolibrary.org/obo/PR_000036822
Ontology Information
PRO ID PR:000036822 Show OBO stanza
PRO name E protein
Synonyms
PRO-short-label: EXACT: DenV-E
Other: EXACT: Envelope protein E
Definition A dengue virus genome polyprotein proteolytic cleavage product that is a structural protein containing two alpha-helices (EH1 and EH2) at the C-terminus and two transmembrane domains (ET1 and ET2) of the dengue virus RNA genome. It contains two N-linked glycosylation sites, at Asn-67 and Asn-153. Example: UniProtKB:P29990, 281-775, Asn-347/Asn-433, MOD:00160. [PMID:17459925, PMID:23300717, PRO:DAN, PRO:ES]
Comment Requested by=IDODEN. The E protein is responsible for eliciting the majority of the protective dengue virus antibody response. It covers the virion surface arranged in anti-parallel dimers containing three structural and antigenic domains [PMID:22709350, PRO:ES].
PRO Category modification
Parent PR:000036818 dengue virus genome polyprotein proteolytic cleavage product
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

DenV-E forms found in complexes
DenV-E Component Complexes
PR:000036822 DenV-E PR:000036999 E protein dimer
PR:000036822 DenV-E PR:000036823 prM-E complex

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