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Protein Ontology Report - DenV-NS1

PR:000036824 -
Ontology Information
PRO ID PR:000036824 Show OBO stanza
PRO name NS1
PRO-short-label: EXACT: DenV-NS1
Other: EXACT: non-structural protein 1
Definition A dengue virus genome polyprotein proteolytic cleavage product that is the N-terminal most non-structural protein within the dengue virus genome polyprotein. Example: UniProtKB:P29990, 776-1127, Asn-905/Asn-982, MOD:00160. [PRO:ES]
Comment Requested by=IDODEN. NS1 is a secreted glycoprotein that is absent from viral particles but accumulates in the supernatant and on the plasma membrane of cells during infection. Because it derives from a glycosylated precursor it includes two N-glycosylated residues at Asn-130 and Asn-207. [PMID:18052531, PRO:ES].
PRO Category modification
Parent PR:000036818 dengue virus genome polyprotein proteolytic cleavage product
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

DenV-NS1 forms found in complexes
DenV-NS1 Component Complexes
PR:000036824 DenV-NS1 PR:000037002 NS1 dimer
PR:000037000 DenV-NS1/sugar(+) PR:000037005 NS1 hexamer, with complex sugar attached
PR:000037000 DenV-NS1/sugar(+) PR:000037003 NS1 dimer, with complex sugar attached
PR:000037001 DenV-NS1/sugar(-) PR:000037004 NS1 dimer, without complex sugar unattached