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Protein Ontology Report - m-LPS:sCD14

PR:000037467 -
Ontology Information
PRO ID PR:000037467 Show OBO stanza / GPI
PRO name LPS:secreted CD14 complex (mouse)
PRO-short-label: EXACT: m-LPS:sCD14
Other: EXACT: sCD14/LPS complex (mouse)
Definition An LPS:secreted CD14 complex whose components are encoded in the genome of mouse. [PMID:10601848, PMID:18606699]
Comment Requested by=TLR. Note: PMID:10601848 shows evidence for complex in Figure 1, and indicates in the discussion that it uses the high M(r) form of sCD14. However, the authors show that the specific form of sCD14 found has the same M(r) as the mCD14, which is a hallmark of the shorter form. For this reason we consider the actual form used to be unclear. In PMID:18606699, evidence is indirect from response of endothelial epithelium to LPS with sCD14 depleted mouse plasma compared to normal.
PRO Category organism-complex
Parent PR:000029989 LPS:secreted CD14 complex
Taxon NCBITaxon:10090 Mus musculus
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000037467 PR:000036850 CD14 molecule isoform 1 cleaved and soluble form (mouse) mCD14/iso:1/ClvPrd/soluble A CD14 molecule isoform 1 cleaved and soluble form in mouse. [PRO:DAN]
CHEBI:16412 lipopolysaccharide lipopolysaccharide Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). [fake:1]