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Protein Ontology Report - chick-(MYD88:TIRAP:TLR4actv)

PR:000037475 -
Ontology Information
PRO ID PR:000037475 Show OBO stanza / PAF
PRO name MYD88:TIRAP:activated TLR4 receptor (chicken)
PRO-short-label: EXACT: chick-(MYD88:TIRAP:TLR4actv)
Other: EXACT: MYD88:MAL:LY96:TLR4:LPS complex (chicken) | MYD88:MAL:activated TLR4 receptor (chicken)
Definition A MYD88:TIRAP:activated TLR4 receptor whose components are encoded in the genome of chicken. [Reactome:R-GGA-433821]
Comment Requested by=TLR.
PRO Category organism-complex
Parent PR:000025784 MYD88:TIRAP:activated TLR4 receptor
Taxon NCBITaxon:9031 Gallus gallus
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000037475 PR:A5HNF6 myeloid differentiation primary response protein MyD88 (chicken) chick-MYD88 A myeloid differentiation primary response protein MyD88 that is encoded in the genome of chicken. [OMA:A5HNF6, PMID:18582498, PRO:CNA] 2
PR:A0A1D5NZX9 lymphocyte antigen 96 (chicken) chick-LY96 A lymphocyte antigen 96 that is encoded in the genome of chicken. [OMA:A0A1D5NZX9, TLR:AMM] 2
PR:Q7ZTG5 Toll-like receptor 4 (chicken) chick-TLR4 A Toll-like receptor 4 that is encoded in the genome of chicken. [PMID:18768894, PMID:20483729, PRO:CNA] 2
PR:Q4U127 Toll-interleukin 1 receptor domain-containing adaptor protein (chicken) chick-TIRAP A Toll/interleukin-1 receptor domain-containing adapter protein that is encoded in the genome of chicken. [OMA:Q4U127, PRO:CNA] 2
CHEBI:16412 lipopolysaccharide lipopolysaccharide Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). [fake:1] 2

Functional Annotation
PRO Term GO Annotation Evidence
MYD88:TIRAP:activated TLR4 receptor (chicken)
acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_25089
acts_upstream_of_or_within GO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_25089
located_in GO:0005886 plasma membrane Reactome:REACT_26615
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005886 plasma membrane PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken)