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Protein Ontology Report - mCEACAM1a/iso:4L/SigPep-/NGlycoAsn+

PR:000044463 - http://purl.obolibrary.org/obo/PR_000044463
Ontology Information
PRO ID PR:000044463 Show OBO stanza / PAF / GPI
PRO name CEACAM1a-4L, signal peptide removed N-glycosylasparagine form (mouse)
Synonyms
PRO-short-label: EXACT: mCEACAM1a/iso:4L/SigPep-/NGlycoAsn+
PRO-proteoform-std: EXACT: UniProtKB:P31809-1, 35-521, MOD:00160
PRO-proteoform-ftid: EXACT: PRO_0000014563, MOD:00160
Other: RELATED: Bgp D glycosylated (mouse) | Bgp1a/4L glycosylated (mouse) | Ceacam1a isoform Long glycosylated (mouse) | Ceacam1a/D1-4L glycosylated (mouse)
Definition A carcinoembryonic antigen-related cell adhesion molecule 1, signal peptide removed form that is the signal cleavage product of isoform Long in mouse and includes at least one N-glycosylasparagine. UniProtKB:P31809-1, 35-521, MOD:00160. [PMID:1648219, PMID:8896983, PRO:KRC, UniProtKB:P31809]
Comment Evidence=(ECO:0000250, based on PMID:1648219). Evidence=(ECO:0000250, based on UniProtKB:P31809). Evidence=(ECO:0000205, based on UniProtKB:P31809). Note: PMID:1648219 shows sequencing of mature N-terminus of Ceacam1 purified from Swiss Webster mice, but not specific to a sequence isoform; PMID:8896983 shows immunoblot showing native size of purified BgpA (Bgp1/4S) and BgpD (Bgp1/2S) and after N-glycanase treatment (Fig 2A).
PRO Category organism-modification
Parent PR:000018399 carcinoembryonic antigen-related cell adhesion molecule 1, signal peptide removed form
Taxon NCBITaxon:10090 Mus musculus
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044463
mCEACAM1a/iso:4L/SigPep-/NGlycoAsn+
MOD:00160
acts_upstream_of_or_within GO:0042130 negative regulation of T cell proliferation MGI:3693042, PMID:17081782
acts_upstream_of_or_within GO:0032703 negative regulation of interleukin-2 production MGI:3693042, PMID:17081782
acts_upstream_of_or_within GO:0042130 negative regulation of T cell proliferation MGI:5451119, PMID:23123061
located_in GO:0009897 external side of plasma membrane MGI:3693042, PMID:17081782
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0009897 external side of plasma membrane PR:000044463 mCEACAM1a/iso:4L/SigPep-/NGlycoAsn+
MOD:00160
MGI:3693042, PMID:17081782

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